Chlamydia pneumoniae and atherosclerosis

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Chlamydia pneumoniae and atherosclerosis.

OBJECTIVE To review the literature for evidence that chronic infection with Chlamydia pneumoniae is associated with atherosclerosis and acute coronary syndromes. DATA SOURCES MEDLINE and Institute of Science and Information bibliographic databases were searched at the end of September 1998. Indexing terms used were chlamydi*, heart, coronary, and atherosclerosis. Serological and pathological ...

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Atherosclerosis and Chlamydophila (chlamydia) Pneumoniae

The concept that atherosclerosis was induced by environmental factors such as smoking and high fat intake was perturbated when inflammation was found to be prominent in atherosclerotic lesions. Chlamydophila pneumoniae but also other microbes inducing chronic endothelial infections have been implicated, particularly cytomegalovirus (CMV) and the gastric pathogen Helicobacter pylori. Large sero-...

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Chlamydia pneumoniae infection and atherosclerosis: methodological considerations.

Atherosclerosis: Methodological Considerations To the Editor: In contrast to several previously published studies,1–3 the one by Caligiuri et al4 failed to observe an accelerating effect of Chlamydia pneumoniae infection on atherosclerotic lesion development in apolipoprotein E–deficient mice. There are several critical differences in experimental design that likely account for these contrastin...

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Chlamydia pneumoniae, antibiotic treatment, and early atherosclerosis.

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The relation between Chlamydia pneumoniae and atherosclerosis.

A causative role of infection in the pathogenesis of atherosclerosis was first proposed in 1908 by Sir William Osler.' Although originally this view was not widely accepted, there is now renewed interest in the contributions made by common chronic infections to the pathogenesis and progression of coronary artery disease (CAD). The modemr "response to injury" model of atherosclerosis acknowledge...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1999

ISSN: 0021-9746

DOI: 10.1136/jcp.52.5.398b